BDBM50220305 4-(3-(2-(amino(3-hydroxypropylamino)methyleneamino)-2-oxoethyl)-4-(2-chlorophenyl)thiophen-2-yl)-N-(cyclopropylmethyl)benzamide::CHEMBL237493

SMILES OCCCNC(=N)NC(=O)Cc1c(csc1-c1ccc(cc1)C(=O)NCC1CC1)-c1ccccc1Cl

InChI Key InChIKey=SHFCEQRTSOSHGI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220305   

TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50220305(4-(3-(2-(amino(3-hydroxypropylamino)methyleneamino...)
Affinity DataIC50:  140nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed